Reorganization of Somatosensory Cortex Subsequent to Dorsal Column Injury: a Study of the Marmoset and the Squirrel Monkey
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چکیده
For my grandmother, a quiet, dignified woman. iii ACKNOWLEDGEMENTS This work would not have been possible without the financial support of the Christopher and Dana Reeve foundation, and for this I thank them. I would like to thank my advisor Jon Kaas for his support and for his many words of wisdom. He is truly an inspirational man. I thank my committee members Troy Hackett, Sohee Park, and Ford Ebner for their guidance and helpful discussion. I thank Laura Trice for her histological prowess, and Mary Feurtado, our very own monkey whisperer. I thank my lab mates, my family, and my friends for their support and guidance. Many thanks to Halo and Olegovich ,a steady source of laughs, & thank you Oleg, you have been wonderful.
منابع مشابه
Dynamic reorganization of digit representations in somatosensory cortex of nonhuman primates after spinal cord injury.
Somatosensory cortices of adult primates reactivate over time after sensory loss. The time course and the neural mechanisms underlying the cortical reactivation are not well understood. Here we report that longitudinal high-resolution functional magnetic resonance imaging (fMRI) studies on anesthetized squirrel monkeys revealed dynamic reorganizations of digit activations in area 3b, within 2 m...
متن کاملParallel functional reorganizations of somatosensory areas 3b and 1, and S2 following spinal cord injury in squirrel monkeys.
Multiple somatosensory cortices of adult primates reorganize following spinal cord injury, but little is known about the temporal dynamics and inter-areal differences of the reorganization. Using longitudinal high-resolution fMRI in combination with microelectrode recordings and tracer histology, we previously illustrated a two-phase dynamic spatial reorganization of digit representations in ar...
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The primate somatosensory system provides an excellent model system with which to investigate adult neural plasticity. Here, we report immunohistochemical staining data for the GluR1 and GluR2/3 AMPA receptors subunits in somatosensory area 3b 1 week after median nerve compression in adult squirrel monkeys. We find transcortical increases in the staining intensity of GluR1 AMPAR subunits and tr...
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متن کاملReorganization of somatosensory cortical areas 3b and 1 after unilateral section of dorsal columns of the spinal cord in squirrel monkeys.
An incomplete lesion of the ascending afferents from the hand in the dorsal columns of the spinal cord in monkeys is followed after weeks of recovery by a reactivation of much of the territory of the hand representations in primary somatosensory cortex (area 3b). However, the relationship between the extent of the dorsal column lesion and the amount of cortical reactivation has not been clear. ...
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تاریخ انتشار 2011